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HIV Symptoms and Signs Screening Panel (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test evaluates markers that may indicate exposure to HIV, the virus that causes AIDS, by analyzing your blood. It helps determine if you’ve been recently exposed to the virus.

Quick summary

This screening helps identify potential HIV exposure early for prompt medical evaluation.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48549-0
Short code
HIVSIGNSANDSYMPTOMSCHECKLISTSSCPANEL
Synonyms
—
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The panel includes tests for antibodies and antigens that may appear in your blood after HIV exposure. Antibodies are proteins your immune system produces in response to the virus, while antigens are specific viral proteins detected shortly after infection. These tests are designed to detect signs of recent infection, not past exposure.

How the Test Works

Your blood sample is collected and analyzed using immunoassay methods, which detect the presence of HIV antibodies and antigens. These tests are highly sensitive and specific for identifying active HIV infection.

Preparation and Sample Collection

No special preparation is needed. A blood sample is drawn from a vein in your arm by a healthcare professional. The sample is sent to a lab for testing.

When to Consider This Test

This screening panel is recommended for individuals at higher risk of HIV exposure, such as those with multiple sexual partners, unprotected sex, shared needles, or other risk factors. It may also be advised by your healthcare provider if you experience symptoms like fever, fatigue, or unexplained weight loss.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HIV Screening Panel

Frequently asked questions

Why might I need this test?
Your healthcare provider may suggest this test if you have risk factors for HIV or if you notice symptoms that could indicate infection. Early detection allows for timely treatment and management of HIV, improving long-term health outcomes.
What do the results mean?
Positive results indicate potential HIV infection and require immediate medical evaluation. Negative results mean you are not currently infected, but ongoing monitoring may be recommended based on your risk factors.
Can I get false positives or negatives?
While these tests are highly accurate, rare false positives or negatives can occur. If your results are unclear, your doctor may order additional testing for confirmation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy