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Human Leukocyte Antigen (HLA) Typing (B Group) - Serological

Published: August 9, 2026Updated: August 16, 2026

This test identifies specific human leukocyte antigen (HLA) markers on your white blood cells, particularly those in the B group, which play a key role in immune response and organ compatibility.

Quick summary

["This test helps assess immune compatibility for potential organ transplants or certain autoimmune conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13301-7
Short code
HLAABBW
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is HLA Typing Used For?

HLA typing is primarily used to determine compatibility between donors and recipients for organ transplants, such as kidneys or other tissues. It also helps in diagnosing or managing certain autoimmune diseases where specific HLA markers are linked to susceptibility or severity.

How Is This Test Performed?

Blood is drawn from a vein, and the serum/plasma is tested using serological methods to detect the presence of HLA-B antigens. Results are reported as positive or negative for specific markers.

Preparation for the Test

No special preparation is needed. You may eat and drink normally before the test, but inform your healthcare provider about any medications you’re taking, as some may affect results.

What Are Common Results and Interpretation?

Results list which HLA-B markers are present on your blood cells. A full HLA typing panel may include multiple markers, and results are used to guide medical decisions, such as transplant matching or disease management.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HLA-B Typing (Serology)

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend HLA-B typing if you’re a potential transplant candidate, have an autoimmune condition linked to HLA markers, or are being evaluated for tissue compatibility in a medical procedure.
How long does it take to get results?
Results are typically available within 1–2 weeks, depending on laboratory processing times and the complexity of the HLA panel requested.
Can results affect my treatment plan?
Yes, HLA results can influence decisions about organ transplants, immune-suppressive therapies, or tailored treatments for autoimmune diseases based on your specific genetic markers.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy