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Cytomegalovirus (CMV) Antibody Test (IgG and IgM) in Whole Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies against cytomegalovirus (CMV), a common virus that can affect the immune system. It helps determine if your body has ever been exposed to CMV or if you currently have an active infection.

Quick summary

["CMV antibodies help track past or present infection, guiding treatment and monitoring for immune-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95199-6
Short code
HLA-B35 CMV CD8 Cells # Bld FC
Synonyms
HLA-B35 CMV CD8 Cells # Bld FC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects two types of CMV antibodies: IgG (indicating past exposure or long-term immunity) and IgM (suggesting recent infection). These antibodies are found in your blood and help your immune system fight or remember the virus.

Why Might You Need This Test?

Doctors may order this test if you have a weakened immune system (e.g., due to HIV, chemotherapy, or organ transplant), symptoms like fever, fatigue, or swollen lymph nodes, or if you’re pregnant (to check for CMV exposure).

How Is the Test Performed?

A small blood sample is drawn from a vein in your arm. The sample is then tested in a lab to identify CMV antibodies using immunoassay methods.

What Are the Possible Results?

Results may show positive IgG (indicating past infection), positive IgM (possible recent infection), both (active infection), or neither (no prior exposure). Results don’t always match symptoms and should be interpreted by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CMV Antibody Profile

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
Can I have a blood test at home instead of a clinic?
No, this test requires a lab sample collected by a healthcare professional. Home blood tests for CMV antibodies are not standard or FDA-approved for this purpose.
What if my test results are positive for CMV IgM?
A positive IgM result suggests recent CMV infection. Your doctor may recommend additional testing (like PCR) or monitoring to confirm active infection and guide treatment, especially if you have a weakened immune system.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy