Genetic test for high-resolution analysis of donor alleles in a specific genetic marker region (e.g., HLA)
This test helps determine the precise genetic matching of donor alleles (genetic markers) in blood or tissue compatibility studies, often used in organ transplantation or stem cell donation.
["Assists in improving transplant success by refining genetic compatibility analysis."]
Key facts at a glance
- LOINC
- 96622-6
- Short code
- HLA-C Unreslvd Alleles Donr High Res
- Synonyms
- HLA-C Unreslvd Alleles Donr High Res
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- high-resolution
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
This test evaluates specific genetic sequences (alleles) in a donor’s DNA that are critical for organ or tissue compatibility. It provides detailed, high-resolution data on the genetic markers (e.g., HLA types) to assess how well a donor’s cells may match your own.
Why It’s Used in Transplantation
High-resolution HLA testing is essential for organ transplantation, such as kidneys, liver, or bone marrow, to minimize rejection risks. It helps match donors and recipients based on genetic compatibility, improving outcomes for patients.
Common Uses Beyond Transplantation
Beyond transplants, this test may also be used in stem cell donations, genetic research, or specialized medical procedures requiring precise genetic matching for safety and efficacy.
How the Test Works
The test involves analyzing a blood sample (whole blood, plasma, or serum) to extract and sequence donor-specific genetic markers. Advanced techniques like high-performance liquid chromatography (hplc) or similar methods may be used to detect and compare these markers precisely.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
HLA Allele Donor High-Resolution Test
Frequently asked questions
High-resolution HLA testing reduces the risk of transplant rejection by ensuring a closer genetic match between donor and recipient. It also supports personalized medicine approaches where genetic compatibility directly influences treatment success.
What does a high-resolution HLA test involve?
How long does it take to get results from this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy