HLA-DQB1 unresolved alleles
This test checks for certain genetic variations in your immune system’s HLA-DQ genes, which may increase your risk of developing autoimmune conditions like celiac disease.
Genetic screening for immune-related risks may help identify potential health concerns before symptoms appear.
Key facts at a glance
- LOINC
- 96660-6
- Short code
- HLA-DQB1 Unreslvd Alleles Donr High Res
- Synonyms
- HLA-DQB1 Unreslvd Alleles Donr High Res
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- high-resolution
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test looks for specific genetic sequences (alleles) in the HLA-DQ region of your DNA. These sequences are part of your immune system’s protein markers and can influence how your body responds to certain foods or infections.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms of celiac disease (e.g., digestive issues, fatigue), a family history of autoimmune disorders, or if you’re considering certain treatments that could trigger immune reactions.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample (whole blood) for genetic analysis. Results are typically available within days to weeks, depending on lab processing.
What the Results Mean
Positive results indicate the presence of high-risk alleles, which may raise your risk of conditions like celiac disease or other autoimmune disorders. Negative results mean these specific alleles were not detected, but other genetic factors may still apply.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: High-risk alleles in the HLA-DQ region are strongly linked to autoimmune diseases, particularly celiac disease, where the immune system mistakenly attacks gluten. While this test doesn’t diagnose disease, it can inform risk assessment and guide further testing or monitoring.
Short name
HLA-DQ Allele Screening
Frequently asked questions
What does a positive result mean for my health?
How long will it take to get my results?
Can I eat normally before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy