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Hemoglobin A1c (HbA1c) with 24-hour urine collection for total creatinine clearance

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar levels over the past 2–3 months and evaluates how well your kidneys filter waste from your blood over a full day.

Quick summary

["Helps track diabetes management and kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78016-3
Short code
HLA-DRB Low res
Synonyms
HLA-DRB Low res
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
low-resolution
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Blood Sugar Control

HbA1c reflects long-term glucose exposure, giving doctors a clearer picture of how well your diabetes is managed over time. It’s a key tool for adjusting medications or lifestyle strategies to prevent complications like nerve damage or heart disease.

How Kidney Function Is Assessed

Creatinine clearance measures how efficiently your kidneys remove waste from blood. This test helps identify early signs of kidney problems, which can be linked to diabetes or other conditions.

What to Expect Before the Test

For HbA1c: No special prep is needed, but fasting isn’t required. For creatinine clearance: Collect all urine for 24 hours in a container provided by your lab. Drink as much water as you normally do.

What the Results Mean

HbA1c results (typically reported as a percentage) show average blood sugar levels. Creatinine clearance results (in mL/min) indicate kidney function. Together, they help determine if your diabetes treatment is working and if kidney health is stable.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HbA1c + Creatinine Clearance (24h urine)

Frequently asked questions

HbA1c helps detect poor blood sugar control, which can worsen kidney disease. High creatinine clearance values may signal kidney strain, especially in people with diabetes. These tests work together to prevent serious complications like kidney failure or cardiovascular disease.
This test is often used to monitor long-term diabetes management and kidney health in people with diabetes or those at risk for kidney issues.
What does an abnormal HbA1c result mean?
An elevated HbA1c (typically above 7%) suggests poor blood sugar control, which may require adjustments to diet, exercise, or medication. A creatinine clearance below 60 mL/min may indicate early kidney problems, prompting further evaluation by your doctor.
Can I eat or drink anything before the creatinine clearance test?
Yes, you can eat and drink normally. The 24-hour urine collection focuses on measuring waste removal, so hydration is encouraged to support kidney function.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy