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Total Hemoglobin Mass in Red Blood Cells (Serum or Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of hemoglobin (the oxygen-carrying protein in red blood cells) contained within your red blood cells. It helps assess overall red blood cell health and iron status.

Quick summary

["Helps evaluate iron deficiency and red blood cell production efficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39602-8
Short code
Hmtr Epith IgE/IgE total %
Synonyms
Hmtr Epith IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, pale skin, shortness of breath, or unexplained anemia. It’s also used to monitor conditions like chronic kidney disease, certain cancers, or during pregnancy.

What to Expect Before the Test

No special preparation is needed. A blood sample will be taken from a vein in your arm, similar to other routine blood tests. The process is quick and usually painless.

How the Test Results Are Interpreted

Results are compared to a reference range based on age, sex, and overall health. While this test alone doesn’t provide specific iron levels, it can help identify whether your red blood cells contain enough hemoglobin for normal function.

Common Reasons for Abnormal Results

Low results may suggest conditions like iron deficiency anemia, chronic blood loss, or certain genetic disorders. High results could indicate polycythemia (overproduction of red blood cells) or dehydration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Hemoglobin Mass in RBCs

Frequently asked questions

How often will I need this test?
The frequency depends on your health condition. If you have a chronic illness like anemia or kidney disease, your provider may order it regularly. Otherwise, it’s often done as needed for specific symptoms or investigations.
What does a low result mean for my health?
A low result may indicate your red blood cells aren’t carrying enough oxygen, which can cause fatigue, weakness, or pale skin. Your provider will discuss next steps, such as dietary changes, supplements, or further testing to identify the cause.
Can I influence this test result with my diet?
Yes, diet can affect red blood cell health. Eating foods rich in iron (like lean meats, leafy greens, or fortified cereals) and vitamin C (which helps iron absorption) may support normal hemoglobin levels. Avoid excessive caffeine or alcohol, as they can interfere with iron absorption.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy