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Hemoglobin A1c (HbA1c) with 24-hour urine collection for total creatinine clearance

Published: August 9, 2026Updated: August 16, 2026

This test measures your average blood sugar over the past 2–3 months and evaluates how well your kidneys filter waste from your blood over 24 hours.

Quick summary

["Helps track diabetes management and kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72160-5
Short code
Holo-TC-II Ser-sCnc
Synonyms
Holo-TC-II Ser-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Blood Sugar Control

HbA1c reflects your blood glucose levels over time, giving doctors a clearer picture of how well your diabetes is managed. It’s not affected by short-term fluctuations like meals or stress.

How Kidney Function Is Assessed

The 24-hour urine creatinine clearance test estimates how well your kidneys remove waste. This helps identify kidney issues that might affect how your body processes medications or other substances.

What to Expect Before the Test

For HbA1c: No special prep is needed. For creatinine clearance: Collect all urine for 24 hours in a container. Drink normal fluids unless instructed otherwise.

Common Causes for Testing

Doctors may order this test if you have diabetes, kidney problems, or if your blood sugar or kidney function needs monitoring.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: HbA1c provides long-term glucose control data, while creatinine clearance assesses kidney function. Together, they help diagnose or manage conditions like diabetes, kidney disease, or metabolic disorders.

Short name

HbA1c + Creatinine Clearance (24h urine)

Frequently asked questions

What does an abnormal HbA1c result mean?
An elevated HbA1c suggests poor blood sugar control, which may require adjustments to diet, exercise, or medication. A low result could indicate well-controlled diabetes, but further discussion with your doctor is needed.
How often should I get this test?
Your doctor will determine frequency based on your health. Typically, HbA1c is checked every 3–6 months for diabetes management, while creatinine clearance may be checked if kidney function is being monitored.
Can diet or exercise affect these test results?
HbA1c reflects long-term trends and isn’t directly influenced by short-term diet or exercise. Creatinine clearance depends on kidney function, which may be affected by hydration status or certain medications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy