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Homeostatic Model Assessment of Insulin Resistance (HOMA-IR)

Published: July 27, 2026Updated: August 25, 2026

HOMA-IR measures the degree of insulin resistance by assessing the balance between glucose and insulin levels in the body.

Quick summary

HOMA-IR is an index used to diagnose insulin resistance.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
index
Clinical utility
diagnostic
Result kind
semi_quantitative
FDA-cleared
Roche HOMA-IR Calculated, Abbott HOMA-IR
interpretation: {"text":"Normal insulin sensitivity.","label":"0–2.5"}; {"text":"Indicates insulin resistance, requiring further evaluation and management.","label":">2.5"}

HOMA-IR is a mathematical model that estimates insulin resistance based on fasting glucose and insulin levels. It is widely used in clinical settings to assess metabolic health.

A higher HOMA-IR value indicates greater insulin resistance, which is often associated with conditions like type 2 diabetes, obesity, and metabolic syndrome.

The reference range for HOMA-IR is typically between 0 and 2.5, with values above this range suggesting increased risk for insulin resistance and related metabolic disorders.

Frequently asked questions

What is a normal HOMA-IR value?
A normal HOMA-IR value is typically between 0 and 2.5.
How is HOMA-IR calculated?
HOMA-IR is calculated using the formula: (fasting insulin µU/mL × fasting glucose mmol/L) / 22.5.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy