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Hemodialysis End-of-Period Urea and Creatinine Profile (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures your blood levels of urea nitrogen and creatinine to check how well your kidneys are filtering waste during hemodialysis.

Quick summary

Helps ensure your dialysis removes enough waste while keeping your levels safe for your health.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
64355-1
Short code
HOMEPATIENTSHEMODIALYZINGATENDOFREPORTINGPERIOD
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Urea nitrogen (blood urea nitrogen, or BUN) and creatinine are waste products your kidneys normally filter from your blood. During dialysis, these levels can rise if the process isn’t working as expected. Your doctor uses these measurements to adjust your dialysis settings to maintain balance in your body fluids and electrolytes.

Why It’s Done During Hemodialysis

At the end of each dialysis session, these tests help confirm that your kidneys are being supported effectively. If levels are too high, it may indicate that too much fluid or waste isn’t being removed, or that your blood flow through the dialysis machine isn’t optimal. If levels are too low, it might suggest excessive fluid removal or that your kidneys are still filtering waste too slowly.

How It’s Performed

A small blood sample is taken from your arm or hand at the end of your dialysis session. The sample is sent to a lab to measure the concentration of urea nitrogen and creatinine in your blood plasma or serum.

What the Results Mean

Your results will be compared to your baseline or previous readings to see if your dialysis is working as intended. Your doctor will discuss any changes needed to your dialysis plan based on these findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Dialysis Monitoring

Frequently asked questions

Why might my urea or creatinine levels be checked at the end of dialysis?
Your doctor may check these levels at the end of dialysis to ensure your body isn’t retaining too much waste or fluid. Abnormally high levels could mean your dialysis isn’t removing enough waste, while very low levels might indicate too much fluid was removed during the session.
What happens if my levels are too high?
If your levels are too high, your doctor may adjust your dialysis time, fluid intake restrictions, or medication to help your body stay balanced. This could include increasing dialysis sessions, monitoring your diet more closely, or modifying your medications.
Can I eat or drink anything before this test?
You may eat and drink normally before this test, as it’s performed at the end of your dialysis session. However, always follow your healthcare team’s specific instructions for your routine.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy