Skip to content

Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions.

Quick summary

["IgE levels help identify allergies or immune responses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40997-9
Short code
Honey bee IgE/IgE total %
Synonyms
Honey bee IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgE Measure?

IgE (Immunoglobulin E) is a protein produced by your immune system in response to allergens like pollen, dust, or certain foods. High levels of IgE can indicate allergies, asthma, or other allergic conditions. This test helps doctors determine if you have an allergic reaction or an immune system issue related to IgE.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, rashes, or breathing difficulties that suggest allergies. It can also be used to monitor conditions like allergic asthma or chronic urticaria (hives).

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is then sent to a lab where it is analyzed to measure the IgE levels. The test usually takes a few days to return results.

What Do the Results Mean?

Results are not given in a single number range but rather as a comparison to your baseline or reference values. High IgE levels may suggest allergies or other immune-related conditions, while normal levels do not necessarily rule out allergies. Your doctor will interpret the results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

IgE levels are important for diagnosing and managing allergic diseases. Elevated IgE can indicate hypersensitivity to specific allergens, guiding treatment plans such as allergy testing, immunotherapy, or avoiding known triggers. Low IgE levels may be less concerning for allergies but can sometimes be linked to other immune conditions.

Short name

IgE Total

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels are often linked to allergies, such as reactions to pollen, pet dander, or certain foods. They can also be associated with conditions like asthma, eczema, or parasitic infections. Chronic stress or certain medications may also play a role.
What if my IgE levels are high?
If your IgE levels are high, your doctor may recommend allergy testing (like skin prick tests or blood tests for specific allergens) to identify triggers. Treatment may include avoiding allergens, using antihistamines, or undergoing allergy immunotherapy (allergy shots). Follow-up tests may be needed to monitor your response to treatment.
Can IgE levels be affected by diet?
Diet alone does not typically change IgE levels, but certain foods may trigger allergic reactions that could indirectly affect symptoms. If you suspect food allergies, discuss dietary changes with your doctor, who may recommend elimination diets or allergy testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy