Human Papillomavirus (HPV) Type 16 and 18 Antibody, Qualitative (Serum/Plasma)
This test checks for antibodies against specific types of human papillomavirus (HPV) that may be linked to certain cancers, including cervical, vaginal, vulvar, penile, anal, and oropharyngeal cancers.
["It helps assess your immune response to HPV types 16 and 18, which are high-risk strains associated with long-term health risks if not managed properly."]
Key facts at a glance
- LOINC
- 50596-6
- Short code
- HPA-1a Bld
- Synonyms
- HPA-1a Bld
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have a history of HPV-related cancers, persistent abnormal Pap test results, or if you are at higher risk due to factors like smoking, weakened immune system, or exposure to HPV. It can also be part of monitoring for individuals who have received HPV vaccines.
What to Expect Before the Test
No special preparation is needed. The blood sample is typically drawn from a vein in your arm. You may experience a slight pinch or discomfort, but it usually lasts only a few seconds.
What the Test Results Mean
A positive result indicates your immune system has detected and produced antibodies against HPV types 16 and 18. This does not mean you currently have an active infection but suggests prior exposure. The presence of these antibodies may be relevant for monitoring cancer risk or vaccine effectiveness.
Common Uses and Limitations
This test is primarily used for screening, monitoring, or research purposes related to HPV-related cancers. It is not a diagnostic test for active HPV infection or immediate detection of cancer. Results should always be interpreted by a healthcare provider in the context of your medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Antibodies against HPV types 16 and 18 are associated with an increased risk of developing certain cancers. While the presence of these antibodies does not confirm cancer, it can be useful in assessing risk, guiding surveillance, or evaluating the immune response to HPV vaccines. Regular follow-up with a healthcare provider is essential for personalized care.
Short name
HPV 16/18 Antibody Test
Frequently asked questions
What does a positive result mean?
Can this test detect active HPV infection?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy