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Hemoglobin A1c (HbA1c) measured by high-performance liquid chromatography (HPLC)

Published: August 9, 2026Updated: August 16, 2026

This test measures the percentage of hemoglobin that is coated with sugar, reflecting your average blood sugar levels over the past 2–3 months.

Quick summary

["HbA1c helps doctors track diabetes control and long-term blood sugar health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77062-8
Short code
HPD Fam Mut Anl Bld/T
Synonyms
HPD Fam Mut Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What HbA1c Tests Measure

HbA1c reflects the amount of glucose (sugar) that has attached to hemoglobin, the protein in red blood cells that carries oxygen. This attachment is a stable marker of your blood sugar levels over time, providing insight into how well your body manages glucose without daily fluctuations.

Why It’s Used in Diabetes Care

Doctors use HbA1c to assess long-term diabetes management, helping to identify trends in blood sugar control that aren’t visible from a single blood test. It’s a key tool for adjusting treatment plans, such as medication or diet.

How It’s Done

A small blood sample is taken from your arm, usually during a routine visit. The sample is processed using HPLC to measure the percentage of hemoglobin bound to sugar, with results reported as a percentage.

What Normal Results Mean

While reference ranges vary by lab, HbA1c results are often categorized into general health categories (e.g., normal, prediabetes, diabetes) rather than specific numeric ranges. Your doctor will interpret results in the context of your health and treatment goals.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

HbA1c is critical for diagnosing diabetes (typically ≥6.5%) and monitoring prediabetes (4.5%–5.9%). It also helps detect complications like nerve damage or kidney issues by revealing chronic blood sugar exposure. Some conditions (e.g., anemia) can affect HbA1c, so results should be discussed with your provider.

Short name

HbA1c

Frequently asked questions

How often should I get an HbA1c test?
Typically, people with diabetes get tested every 2–3 months to track progress. Your doctor may adjust frequency based on your treatment plan, blood sugar goals, or health status.
Can HbA1c results change if I’ve recently eaten or exercised?
No, HbA1c reflects long-term blood sugar trends and isn’t influenced by short-term diet or activity. However, fasting may be required for some labs to ensure accurate results.
What if my HbA1c is higher than expected?
A higher HbA1c may indicate poor diabetes control or undiagnosed conditions like prediabetes. Your doctor will review your results, lifestyle, and treatment plan to determine next steps, such as adjusting medications or improving habits.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy