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Human Immunodeficiency Virus Type 2 Antibody Screening by Serological Test

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to Human Immunodeficiency Virus Type 2 (HIV-2), a virus that can weaken your immune system. It helps determine if you’ve been exposed to the virus.

Quick summary

["This screening helps identify potential HIV-2 infection early for further evaluation and care."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24220-6
Short code
HPIV2 Ab sp1 Titr Ser CF
Synonyms
HPIV2 Ab sp1 Titr Ser CF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
comp-fix
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have risk factors for HIV-2 infection, such as unprotected sex with multiple partners, sharing needles, or living in regions where HIV-2 is more common. It may also be part of routine testing in certain healthcare settings.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, usually in your arm. You may feel a small pinch, but it typically takes only a few minutes.

What the Test Results Mean

A positive result means your blood contains antibodies to HIV-2, indicating past or possible current infection. A negative result means no detectable antibodies were found in this test. Follow-up testing may be needed to confirm results.

What Happens Next

If your test is positive, your healthcare provider will discuss next steps, which may include additional testing to confirm the diagnosis and determine your health needs.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV-2 Antibody Screen

Frequently asked questions

Early detection of HIV-2 infection is crucial for managing the virus and preventing complications. This screening helps healthcare providers monitor and support individuals at risk, ensuring timely treatment and care to improve long-term health outcomes.
What does a positive result mean?
A positive result suggests you may have been exposed to HIV-2. This does not confirm infection immediately, so further testing is needed to determine if you have the virus. Your healthcare provider will guide you on next steps, including possible follow-up tests.
Can I still be at risk if my test is negative?
Yes, a negative result means no detectable antibodies were found in this test. However, HIV-2 can take time to develop antibodies after exposure. If you have risk factors, continue practicing safer behaviors and discuss ongoing monitoring with your healthcare provider.
If you have risk factors for HIV-2, your healthcare provider may recommend regular testing based on your individual situation. Follow their advice for the best protection and care. Testing frequency can vary depending on your exposure risks and overall health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy