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Human Immunodeficiency Virus (HIV) Antibody Screening by Immunoassay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the human immunodeficiency virus (HIV), which your body produces in response to infection. It helps determine if you have been exposed to HIV.

Quick summary

["This screening helps identify potential HIV exposure for further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15394-0
Short code
HPIV3 IgG Ser Ql
Synonyms
HPIV3 IgG Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for specific antibodies in your blood that your immune system makes when it encounters HIV. These antibodies are a sign that your body has recognized the virus, though infection may not yet be active.

How the Test Works

Your blood sample is tested using an immunoassay method, which detects the presence of HIV antibodies. This method is highly sensitive and designed to catch early signs of exposure.

Why It Matters

Finding HIV early is crucial because it allows for timely medical care, treatment, and support. Early detection helps manage the virus effectively and reduces the risk of spreading it to others.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into your arm to draw blood. If you are pregnant, breastfeeding, or have certain conditions, let your healthcare provider know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HIV Antibody Screen

Frequently asked questions

Why was this test ordered?
Your healthcare provider may recommend this test if you have risk factors for HIV, such as unprotected sex, sharing needles, or other behaviors that increase exposure risk. It may also be part of routine screening for certain groups.
What does a positive result mean?
A positive result means your blood test detected HIV antibodies, suggesting you may have been exposed to HIV. You will need follow-up testing, such as a confirmatory test, to confirm the result and begin appropriate care.
What does a negative result mean?
A negative result means your blood test did not detect HIV antibodies at this time. However, HIV can sometimes take weeks or months to produce detectable antibodies. If you have risk factors, follow-up testing may still be recommended.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy