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Human Papillomavirus (HPV) Genotyping by Cytology (Liquid-Based) from Cervical Specimen

Published: August 9, 2026Updated: August 16, 2026

This test identifies specific types of human papillomavirus (HPV) that may be present in your cervical cells. It helps determine which HPV strains are causing changes in your cervix, which can inform decisions about further screening or treatment.

Quick summary

["HPV genotyping helps guide personalized cervical cancer prevention and management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101822-5
Short code
HPV Cyto HR genotypes Pnl Cvx
Synonyms
HPV Cyto HR genotypes Pnl Cvx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

HPV is a common virus that can cause changes in cervical cells, increasing the risk of precancerous or cancerous growths. Certain HPV types (like HPV 16 and 18) are linked to higher risks of cervical cancer. This test helps doctors identify which HPV types are present to tailor your care.

How the Test Works

Your healthcare provider collects a sample of cervical cells using a special brush or swab. These cells are then processed into a liquid-based preparation for testing. The test analyzes the genetic material (DNA) of HPV in your sample to identify specific HPV genotypes.

Preparation for the Test

No special preparation is needed for this test. You may have a pelvic exam or a simple cervical swab during a routine gynecological visit. Avoid sexual activity, douching, or using vaginal products 24 hours before the test.

What to Expect After the Test

After the test, you’ll receive results from your healthcare provider. If HPV is detected, they may recommend additional tests (like a Pap smear or colposcopy) to check for cell changes or precancerous conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HPV Genotyping Test

Frequently asked questions

What does it mean if HPV is detected?
If HPV is found, it does not automatically mean you have cancer. Many people are infected with HPV but never develop serious health issues. However, certain HPV types can cause long-term changes in cervical cells. Your doctor will discuss next steps based on your test results and overall health.
How often should I get this test?
The frequency depends on your age, medical history, and risk factors. Typically, women with normal Pap smears and no high-risk HPV types may be monitored every 3 years. Women with abnormal findings or higher-risk HPV types may need more frequent testing or follow-up.
Can HPV be cured?
Yes, some HPV infections clear on their own, especially low-risk types. High-risk HPV types may require ongoing monitoring or treatment if precancerous changes are detected. Your doctor will recommend the best approach for your situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy