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Hemoglobin A1c (HbA1c) with 24-Hour Urine Collection for Total Renal Excretion Rate

Published: August 9, 2026Updated: August 16, 2026

This test measures your long-term blood sugar levels (HbA1c) and evaluates how much glucose your kidneys excrete over 24 hours.

Quick summary

["Helps track diabetes management and kidney function together."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99123-2
Short code
HRTV NAb Titr Spec Nt
Synonyms
HRTV NAb Titr Spec Nt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
neut
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why HbA1c Matters

HbA1c reflects your average blood sugar levels over the past 2–3 months, giving doctors a clearer picture of how well your diabetes is controlled. It’s not affected by short-term fluctuations like meals or stress.

Understanding Kidney Glucose Handling

Your kidneys filter glucose from your blood and excrete it in urine. This test checks how much glucose your body removes, which can help assess kidney function and how well your body handles glucose over time.

How This Test Works

Your blood is tested for HbA1c (via standard immunoassay), and a 24-hour urine sample is collected to measure total glucose excretion. Results help balance diabetes care with kidney health.

What the Results Mean

HbA1c results alone show average blood sugar trends, while urine excretion data can reveal kidney strain from glucose overload. Together, they provide a fuller picture of metabolic and renal health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated HbA1c suggests poor diabetes control, while high urine glucose excretion may indicate kidney issues or excessive glucose intake. These tests work together to guide treatment adjustments, such as diet, medication, or kidney monitoring.

Short name

HbA1c + Urine Total Excretion Rate

Frequently asked questions

What does an abnormal HbA1c result mean?
An abnormal HbA1c (typically outside the 5.7%–6.4% range for prediabetes or above 6.5% for diabetes) may signal uncontrolled blood sugar. Your provider will discuss next steps, like adjusting medications or lifestyle changes.
Does this test require fasting?
No fasting is needed for HbA1c, but a 24-hour urine collection should be complete (all urine voided in that period). Your lab will provide instructions to ensure accuracy.
How often should I get this test?
Typically recommended every 3–6 months for diabetes management, depending on your blood sugar control and kidney health. Your healthcare team will determine the best schedule for you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy