Hspabserpliaacnc
This blood test measures antibodies against heat shock protein 60 (HSP60), which may be related to heart and blood vessel health.
{"The test checks for immune proteins that target HSP60, a protein found in cells","It may help evaluate risk for heart disease and certain autoimmune conditions","Results are reported as positive or negative (or as a numerical value)","The test uses a blood sample taken from a vein in your arm","Abnormal results may need follow-up testing to determine the cause"}
Key facts at a glance
- LOINC
- 68934-9
- Short code
- HSP60 Ab
- Synonyms
- HSP Ab SerPl IA-aCnc
- Category
- cardiac
- Sample
- serum
- Container
- Serum separator tube (SST) or plain red top tube
- Units
- N/A
- Ref low
- 10
- Ref high
- 20
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–99 years
- Method
- Immunoassay
- CPT
- 86625
- SNOMED
- 413431009
- Specimen volume
- 1.0-2.0 mL serum minimum
- Stability
- Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C or below): 30 days
- Hemolysis max
- 50
- Lipemia max
- 300
- Icterus max
- 20
- TAT
- 72–168 hours
- Order
- routine
What is this test?
The Heat Shock Protein 60 (HSP60) Antibody test is a blood test that detects whether your immune system is producing antibodies against a specific protein called heat shock protein 60. Normally, HSP60 is found inside cells where it helps other proteins fold correctly. However, when the immune system sees this protein as "foreign," it can produce antibodies against it. This test measures those antibodies in your blood.
Why might I need this test?
This test is primarily used in research and specialized clinical settings to help evaluate: cardiovascular disease risk, particularly atherosclerosis (hardening of the arteries); certain autoimmune conditions where the immune system mistakenly attacks the body's own tissues; and inflammatory conditions that may affect the heart and blood vessels. Your doctor may order this test if you have symptoms or risk factors for heart disease, or if they suspect an autoimmune component to your condition.
How is the test performed?
A healthcare professional will draw a small amount of blood from a vein in your arm. The blood sample is then sent to a laboratory where it is analyzed using a technique called immunoassay, which can detect and measure the amount of HSP60 antibodies present. You do not need to fast or make any special preparations before this test.
What do the results mean?
Results are typically reported as either positive (antibodies detected) or negative (no antibodies detected), or as a numerical value with a reference range. A positive result means that antibodies against HSP60 were found in your blood. This may indicate: an increased risk for cardiovascular disease; an autoimmune response that could be contributing to inflammation in blood vessels; or other inflammatory conditions. However, the presence of these antibodies alone does not diagnose a specific condition. Your doctor will interpret the results together with your symptoms, medical history, and other test results.
Reference range
Negative: < 10 AU/mL; Borderline: 10-20 AU/mL; Positive: > 20 AU/mL (assay-dependent)N/A
No special preparation required. Fasting is not mandatory but avoid hemolysis. Inform laboratory of immunosuppressive therapy or recent immunotherapy.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Is this test painful?
Do I need to fast before this test?
Can this test diagnose heart disease?
What happens if my result is positive?
Are there any risks to having this test?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 10, 2026. · Read our editorial policy