Herpes Simplex Virus Type 1 Antibody, Qualitative (IgG) by Probe-Based Immunoassay
This test detects antibodies to the herpes simplex virus type 1 (HSV-1), a common virus that can cause cold sores and other infections. It helps determine if your immune system has been exposed to HSV-1.
["This test checks for past exposure to HSV-1, not whether you currently have an active infection."]
Key facts at a glance
- LOINC
- 49385-8
- Short code
- HSV1+2 DNA # Amn NAA+probe
- Synonyms
- HSV1+2 DNA # Amn NAA+probe
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test measures the presence of IgG antibodies against HSV-1. These antibodies develop after your body has been exposed to the virus, usually months or years after initial infection. This is a qualitative test, meaning it only tells you whether antibodies are present or not, rather than how much.
Why Might You Need This Test?
Doctors may order this test if you have a history of cold sores or other HSV-1-related symptoms, if you have concerns about recurrent infections, or if you are planning a pregnancy and need to assess potential risks. It can also be used in certain research or screening contexts.
How Is the Test Performed?
A blood sample is drawn from a vein in your arm. The sample is then processed and tested using a probe-based immunoassay, which detects specific antibodies in your blood. Results are typically available within a few days.
What Are Possible Results?
The test result will be either positive (indicating the presence of HSV-1 antibodies) or negative (indicating no detectable antibodies). A positive result suggests past exposure to HSV-1, but does not confirm an active infection.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV-1 Antibody (IgG) Qualitative
Frequently asked questions
What does a positive result mean?
Can this test be used to diagnose an active HSV-1 infection?
Is this test the same as a cold sore test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy