Herpes Simplex Virus Type 1 (HSV-1) DNA in Saliva by Nucleic Acid Probe Test
This test detects the presence of genetic material from the herpes simplex virus type 1 (HSV-1) in your saliva. It helps determine if you have an active infection or have been exposed to the virus.
["This test can help diagnose or monitor herpes simplex virus type 1 infections."]
Key facts at a glance
- LOINC
- 87431-3
- Short code
- HSV 1+2 DNA Pnl Spec NAA+probe
- Synonyms
- HSV 1+2 DNA Pnl Spec NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual rashes in your mouth, lips, or genitals that could be caused by HSV-1. It may also be used to confirm a diagnosis in cases where symptoms are unclear or if you have recurrent outbreaks. Additionally, it could be part of screening for individuals with certain risk factors or conditions linked to HSV-1.
What to Expect Before the Test
No special preparation is needed for this test. You will provide a saliva sample, usually collected by gently rubbing your saliva into a collection device. This is a quick and painless process.
What Happens During the Test
The saliva sample is analyzed in a lab to detect the genetic material of HSV-1. The test uses a probe to identify the virus’s DNA, which helps confirm if an infection is present.
What the Results Mean
A positive result indicates the presence of HSV-1 DNA in your saliva, suggesting you have an active infection or recent exposure. A negative result means the virus was not detected in the sample at the time of testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
HSV-1 is a common virus that can cause cold sores and other infections. Detecting HSV-1 DNA in saliva helps healthcare providers diagnose infections, manage outbreaks, and guide treatment decisions. It can also be useful in research or for monitoring individuals with recurrent symptoms or specific conditions related to HSV-1.
Short name
HSV-1 DNA Saliva Probe Test
Frequently asked questions
How long does it take to get the results of this test?
Can I take anything to make the test more accurate?
Is this test different from a blood test for HSV-1?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy