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Herpes Simplex Virus Type 1 (HSV-1) Immunoglobulin G Antibody (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against HSV-1, a common virus that can cause cold sores and other infections. It helps assess past exposure to the virus.

Quick summary

["This test checks for immunity to HSV-1 through antibody detection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44481-0
Short code
HSV1+2 IgG CSF Ql
Synonyms
HSV1+2 IgG CSF Ql
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

This test is done to help your healthcare provider learn more about your overall health, look for possible conditions early, and guide decisions about any treatment or follow-up care you may need.

Your healthcare provider may order this test if you have symptoms of HSV-1 infection, such as cold sores, or if you have a history of recurrent infections. It can also be used to evaluate immunity in individuals who have been exposed to the virus or for research purposes.

The test involves a simple blood draw, during which a trained professional cleans your skin, collects a small sample from a vein in your arm, and applies a bandage; the whole process usually takes only a few minutes.

A blood sample is drawn from a vein in your arm. The serum portion of the blood is tested for HSV-1 IgG antibodies using an immunoassay method. This test does not detect active infection but rather indicates past exposure.

Doctors typically use the results to confirm or rule out a specific condition, monitor how well a treatment is working over time, and decide whether any additional testing or follow-up care is needed.

Results can confirm past exposure to HSV-1, which may be useful for monitoring immunity, especially in individuals at higher risk of infection or those undergoing immune-suppressing treatments.

A positive result usually means that the substance, germ, or condition the test was designed to detect was found in your sample, and your healthcare provider may recommend further testing or begin treatment.

A positive result means your body has produced antibodies against HSV-1, suggesting you have been exposed to the virus at some point. This does not indicate an active infection but rather immunity.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody

Frequently asked questions

Can this test be used to diagnose an active HSV-1 infection?
No, this test does not diagnose an active infection. It only indicates past exposure through antibody presence. For diagnosing active HSV-1, other tests such as viral culture or PCR are typically used.
How long does it take to get results from this test?
Test results are usually available within 24 to 48 hours, depending on the laboratory’s processing time.
Does this test require fasting?
No, fasting is not required for this blood test. You may eat and drink as you normally would before your appointment unless your healthcare provider gives you different instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy