Herpes Simplex Virus Type 1 (HSV-1) Immunoglobulin G Antibody (Serum)
This test measures the presence of antibodies against HSV-1, a common virus that can cause cold sores and other infections. It helps assess past exposure to the virus.
["This test checks for immunity to HSV-1 through antibody detection."]
Key facts at a glance
- LOINC
- 44481-0
- Short code
- HSV1+2 IgG CSF Ql
- Synonyms
- HSV1+2 IgG CSF Ql
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
This test is done to help your healthcare provider learn more about your overall health, look for possible conditions early, and guide decisions about any treatment or follow-up care you may need.
Your healthcare provider may order this test if you have symptoms of HSV-1 infection, such as cold sores, or if you have a history of recurrent infections. It can also be used to evaluate immunity in individuals who have been exposed to the virus or for research purposes.
The test involves a simple blood draw, during which a trained professional cleans your skin, collects a small sample from a vein in your arm, and applies a bandage; the whole process usually takes only a few minutes.
A blood sample is drawn from a vein in your arm. The serum portion of the blood is tested for HSV-1 IgG antibodies using an immunoassay method. This test does not detect active infection but rather indicates past exposure.
Doctors typically use the results to confirm or rule out a specific condition, monitor how well a treatment is working over time, and decide whether any additional testing or follow-up care is needed.
Results can confirm past exposure to HSV-1, which may be useful for monitoring immunity, especially in individuals at higher risk of infection or those undergoing immune-suppressing treatments.
A positive result usually means that the substance, germ, or condition the test was designed to detect was found in your sample, and your healthcare provider may recommend further testing or begin treatment.
A positive result means your body has produced antibodies against HSV-1, suggesting you have been exposed to the virus at some point. This does not indicate an active infection but rather immunity.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV-1 IgG Antibody
Frequently asked questions
Can this test be used to diagnose an active HSV-1 infection?
How long does it take to get results from this test?
Does this test require fasting?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy