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Herpes Simplex Virus Type 1 (HSV-1) IgG Antibody, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against Herpes Simplex Virus Type 1 (HSV-1) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-1, which can cause cold sores or other infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33293-2
Short code
HSV1+2 IgG CSF Ql IB
Synonyms
HSV1+2 IgG CSF Ql IB
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to HSV-1, which develop after your body has encountered the virus. These antibodies indicate past infection, even if you no longer have active symptoms.

Why Might You Need This Test?

Your healthcare provider may order this test if you have a history of cold sores, recurrent oral or genital sores, or if you’re being evaluated for conditions linked to HSV-1 exposure, such as certain neurological disorders.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. The test is usually done in a lab setting.

What the Results Mean

A positive result means you likely had HSV-1 at some point in your life. A negative result suggests you haven’t been exposed or haven’t developed detectable antibodies yet.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody

Frequently asked questions

Could this test show if I currently have an active HSV-1 infection?
No, this test only detects antibodies, which indicate past exposure. For active infection, your provider may recommend a different test, such as HSV-1 culture or PCR.
What if my results are positive but I’ve never had cold sores?
Even without visible symptoms, some people carry HSV-1 without knowing it. Antibodies can persist long-term after infection, even if symptoms are rare or absent.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy