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Herpes Simplex Virus Type 1 IgG Antibody, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against Herpes Simplex Virus Type 1 (HSV-1) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-1, which can cause cold sores or herpes infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44009-9
Short code
HSV 1+2 IgG Ser IA-Imp
Synonyms
HSV 1+2 IgG Ser IA-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies, which develop after your body has been exposed to HSV-1. These antibodies stay in your system long after the initial infection has cleared, providing a record of past exposure.

Why Might You Need This Test?

A doctor may recommend this test if you have symptoms of HSV-1 infection (like cold sores), if you’ve had close contact with someone who has HSV-1, or if you’re planning pregnancy and need to assess potential risks.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from your arm. The test is usually done in a lab and results are ready within a few days.

What the Results Mean

A positive result means your body has produced antibodies against HSV-1, indicating past exposure. A negative result suggests you may not have been exposed or the test may not have detected antibodies yet.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody

Frequently asked questions

How Long Does It Take to Get Results?
Results are typically available within 2 to 5 business days, depending on lab processing times.
What If My Results Are Positive?
A positive result means you’ve likely had HSV-1 at some point. You’re protected against future infections, but you may still experience cold sores or other symptoms. Your doctor may recommend antiviral medications to manage outbreaks.
Can This Test Detect Active HSV-1 Infection?
No, this test only detects past exposure through antibodies. For diagnosing an active infection, your doctor may use different tests or clinical symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy