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Herpes Simplex Virus Type 1 Immunoglobulin M Antibody, Serum (IgM)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of Immunoglobulin M (IgM) antibodies against Herpes Simplex Virus Type 1 (HSV-1) in your blood. IgM antibodies are typically produced shortly after initial infection.

Quick summary

["IgM antibodies to HSV-1 can help identify recent infection with the virus that causes cold sores or genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110968-5
Short code
HSV1+2 IgM Msmt Ser
Synonyms
HSV1+2 IgM Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgM antibodies specific to HSV-1, which are part of your immune system’s response to the virus. IgM antibodies usually appear within weeks of infection and can stay in your system for months or longer. This test helps determine if you’ve recently been exposed to HSV-1.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual rashes that could be caused by HSV-1, especially if you’ve had similar symptoms in the past. It can also be used to confirm a diagnosis in certain clinical situations.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is sent to a lab where it is tested using an immunoassay method to identify the presence of IgM antibodies against HSV-1.

What Are the Possible Results?

A positive result indicates the presence of IgM antibodies to HSV-1, suggesting recent infection. A negative result means no detectable IgM antibodies were found at the time of testing. Interpretation should be done by your healthcare provider in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgM Antibody to HSV-1

Frequently asked questions

How long does it take to get results from this test?
Results from this test are usually available within 24 to 72 hours, depending on the lab’s processing schedule. Your healthcare provider will contact you once the results are ready.
Can this test detect past infections?
No, this test specifically measures IgM antibodies, which are associated with recent infection. For detecting past infections, other tests like IgG antibody tests may be used, as IgG antibodies can persist longer after infection.
What should I do if I have symptoms like sores or pain?
If you experience symptoms such as sores, pain, or unusual rashes, especially if they appear near your mouth, lips, or genital area, contact your healthcare provider. They may recommend this test or other evaluations to determine the cause of your symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy