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Herpes Simplex Virus Type 1 Immunoglobulin M Antibody, Serum (IgM)

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies to the herpes simplex virus type 1 (HSV-1) in your blood. These antibodies help your immune system recognize and fight the virus.

Quick summary

["This test helps identify if you’ve recently been exposed to HSV-1, which can cause cold sores or genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44008-1
Short code
HSV 1+2 IgM Ser-Imp
Synonyms
HSV 1+2 IgM Ser-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgM antibodies, a type of immune protein produced shortly after your body encounters HSV-1. These antibodies appear early in an infection and can help determine if you’ve been recently exposed to the virus.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like sores, fever, or swollen glands that could be linked to HSV-1 infection, especially if you’ve had recent contact with someone who has herpes.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process takes a few minutes, and you may feel a brief pinch.

What to Expect After the Test

After the blood is drawn, you’ll have a bandage on the site. Mild bruising or soreness is normal but should go away quickly. Avoid strenuous activity for the rest of the day.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgM Antibody

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 72 hours, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I have false-positive or false-negative results?
While rare, false results can occur due to lab errors or other infections. False negatives may happen if the test is taken too early after exposure. If your symptoms persist or worsen, your provider may recommend retesting or additional testing.
Does this test differentiate between HSV-1 and HSV-2?
No, this test only measures antibodies to HSV-1. If your provider suspects HSV-2 infection, they may order a separate HSV-2 IgM or antibody test for clarity.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy