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Herpes Simplex Virus Type 1 IgG Antibody, Serology (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of antibodies against the herpes simplex virus type 1 (HSV-1) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-1, which can cause cold sores or other infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90464-9
Short code
HSV1+2 IgM Ser Ql IA
Synonyms
HSV1+2 IgM Ser Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like cold sores, recurrent mouth ulcers, or if you’ve been exposed to someone with HSV-1. It can also be used in certain diagnostic evaluations or research studies.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is typically done in a lab setting and results are available within a few days.

What the Results Mean

A positive result means your body has produced antibodies against HSV-1, indicating past exposure. A negative result suggests you either haven’t been exposed or the test was taken too early after exposure. This does not confirm active infection.

Common Uses of This Test

This test is often used to confirm past infection with HSV-1, monitor immune responses, or assess exposure in clinical or research settings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Having antibodies to HSV-1 does not mean you currently have an active infection. If you suspect symptoms of an active HSV-1 infection (such as sores or lesions), you should see a healthcare provider for further evaluation, including possible viral testing.

Short name

IgG Antibody to HSV-1

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 2 to 5 business days, depending on your lab’s processing time.
Can this test detect an active infection with HSV-1?
No, this test only detects antibodies, which indicate past exposure. For an active infection, your healthcare provider may order a separate viral test.
Is there any risk or discomfort associated with this blood test?
There is a small risk of bruising or slight discomfort at the injection site. Most people experience minimal or no discomfort.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy