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Herpes Simplex Virus Type 1 IgG Antibody, Immunoassay (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against Herpes Simplex Virus Type 1 (HSV-1) in your blood. These antibodies indicate past exposure to the virus.

Quick summary

["Past infection with HSV-1 may be detected through antibody testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30355-2
Short code
HSV1+2 IgM Ser Ql IF
Synonyms
HSV1+2 IgM Ser Ql IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects IgG antibodies, which develop after an initial infection with HSV-1. These antibodies remain in your blood for a long time, even after the active virus has cleared. This test is not used to diagnose current infection but helps confirm past exposure.

Why It Might Be Ordered

Your healthcare provider may order this test if you have a history of HSV-1 infection, recurrent cold sores, or if you are being evaluated for conditions related to past viral exposure.

What to Expect Before the Test

No special preparation is needed. You may have a blood sample drawn from a vein in your arm. If you are on blood-thinning medication, inform your healthcare provider beforehand.

What to Expect After the Test

After the blood draw, you may feel slight discomfort or bruising at the site. Apply pressure to stop any bleeding. You can resume normal activities immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Antibody to HSV-1

Frequently asked questions

What does a positive result mean?
A positive result means your body has produced antibodies against HSV-1, suggesting you have been exposed to the virus at some point in the past. This does not indicate whether you currently have an active infection.
Can this test detect current HSV-1 infection?
No, this test specifically measures IgG antibodies, which are produced after an initial infection and remain in the body long-term. For diagnosing current infection, other tests or clinical symptoms are typically used.
Is there any risk or discomfort associated with this test?
The test involves a simple blood draw, which may cause slight discomfort or bruising at the site. There are no significant risks associated with this procedure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy