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Herpes Simplex Virus Type 1 Antibody, Qualitative (IgG) – Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the herpes simplex virus type 1 (HSV-1), a common virus that can cause cold sores and other infections. It helps determine if your body has been exposed to HSV-1.

Quick summary

["This test helps assess past infection with HSV-1, which may affect your immune response or risk of certain complications."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94585-7
Short code
HSV 1 + 2 + VZV DNA Pnl Spec NAA+non-prb
Synonyms
HSV 1 + 2 + VZV DNA Pnl Spec NAA+non-prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like cold sores, recurrent infections, or if you’re being evaluated for conditions linked to HSV-1 exposure, such as certain neurological or eye infections. It may also be used in screening for people with weakened immune systems or during pregnancy to assess risk.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is typically done in a lab setting and results are usually available within a few days.

What the Results Mean

A positive result means your body has produced antibodies against HSV-1, indicating past infection. A negative result suggests you may not have been exposed or the infection may be very recent. Antibody levels alone do not indicate the severity or current activity of the virus.

Common Uses and Limitations

This test is primarily used for screening and confirmation of past HSV-1 exposure. It does not diagnose active infection (like cold sores) or measure viral load. Results should be interpreted by a healthcare provider in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV-1 Antibody Screen (IgG)

Frequently asked questions

What questions might you have about this test?
This test is qualitative, meaning it only tells whether antibodies are present or not. It does not provide information about the current viral load or the severity of your infection. If you have symptoms of an active HSV-1 infection, such as sores or flu-like symptoms, you may need additional testing.
How long will it take to get my results?
Results are typically available within 2 to 5 business days, depending on your lab’s processing time. Your healthcare provider will contact you with the results once they are ready.
Can I get this test if I’m pregnant?
Yes, this test can be performed during pregnancy to assess potential exposure to HSV-1. However, if you have active symptoms or concerns about HSV-1, your healthcare provider may recommend additional testing or monitoring.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy