Herpes Simplex Virus Type 1 Antibody, Serum (Qualitative Immunoassay)
This test detects antibodies to the herpes simplex virus type 1 (HSV-1), which can help identify past or current infection with this virus.
["This test helps determine if you’ve been exposed to HSV-1, a common virus that can cause cold sores or other symptoms."]
Key facts at a glance
- LOINC
- 22331-3
- Short code
- HSV1 Ab CSF Ql
- Synonyms
- HSV1 Ab CSF Ql
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test looks for specific antibodies in your serum that your immune system produces in response to HSV-1. These antibodies are signs that your body has recognized and fought off the virus, either from a past infection or potential ongoing exposure.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like cold sores, recurrent mouth ulcers, or if you’re at higher risk for HSV-1 infection, such as during pregnancy or if you have a weakened immune system.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample from a simple venipuncture (blood draw). If you’re pregnant or have a history of bleeding disorders, let your provider know before the test.
What to Expect After the Test
You may experience mild discomfort or bruising at the injection site. Most people return to normal activities immediately. If you have any unusual symptoms or concerns, contact your provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results indicate past exposure to HSV-1, meaning you’ve likely had the virus at some point. While this doesn’t confirm active infection, it can inform treatment decisions, especially in high-risk scenarios like pregnancy. Negative results suggest no detectable antibodies, meaning either you’ve never been exposed or the test was taken too early after exposure. This test is not used to diagnose active herpes outbreaks but can help guide further evaluation.
Short name
HSV-1 Antibody Screen (Serum)
Frequently asked questions
How long does it take to get results?
Can this test detect active herpes outbreaks?
Is this test covered by insurance?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy