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Herpes Simplex Virus Type 1 Antibody, Qualitative (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the herpes simplex virus type 1 (HSV-1), which can help determine past or current infection with this virus.

Quick summary

["This test helps identify if your body has ever been exposed to HSV-1, which can cause cold sores or other infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110921-4
Short code
HSV1 Ab Msmt CSF
Synonyms
HSV1 Ab Msmt CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like cold sores, recurrent mouth ulcers, or if you have been exposed to someone with HSV-1. It may also be used to confirm a diagnosis in certain clinical situations or for monitoring in specific medical contexts.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood, which is then sent to a lab for testing. If you are pregnant or have a history of bleeding disorders, let your provider know before the test.

What the Test Results Mean

A positive result means your body has produced antibodies against HSV-1, indicating past infection. A negative result suggests no detectable antibodies, meaning either you have never been infected or the test was done too early to detect antibodies.

Common Symptoms of HSV-1 Infection

HSV-1 often causes cold sores or fever blisters around the mouth and lips. Some people may also experience flu-like symptoms, such as swollen lymph nodes, headache, or sore throat. Symptoms can vary widely and may not always appear.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 Antibody Test

Frequently asked questions

When might I get false results?
False negatives are possible if the test is done too early after exposure, as antibodies may not develop immediately. False positives are rare but can occur with certain autoimmune conditions or cross-reactivity with other viruses. Always discuss your results with your healthcare provider.
How long does it take to get results?
Test results are typically available within 2 to 5 business days, depending on your lab’s processing time. Your healthcare provider will contact you once the results are ready.
Can I have this test if I’m pregnant?
Yes, this test can be performed during pregnancy. HSV-1 is not typically a concern during pregnancy, but it’s important to confirm infection status if symptoms or exposure is suspected. Always consult your healthcare provider for personalized advice.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy