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Herpes Simplex Virus Type 1 Antibody, Serum (Qualitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the herpes simplex virus type 1 (HSV-1), which can help determine if your body has been exposed to this virus.

Quick summary

["This screening helps assess past infection with HSV-1, often linked to cold sores."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110963-6
Short code
HSV1 Ab Msmt Ser
Synonyms
HSV1 Ab Msmt Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Herpes simplex virus type 1 (HSV-1) is a common virus that can cause cold sores around the mouth and sometimes infections in other parts of the body. This test detects antibodies that your immune system produces after exposure to the virus. Having these antibodies does not necessarily mean you will develop symptoms or that you are currently infected. It simply indicates that your body has encountered the virus at some point.

What to Expect Before the Test

No special preparation is needed for this test. You will provide a blood sample from a vein in your arm. The process is quick and typically painless, though you may feel a brief pinch. If you have a history of blood draws, let your healthcare provider know.

What the Results Mean

If your test result is positive for HSV-1 antibodies, it means your immune system has recognized the virus. This does not confirm an active infection but suggests past exposure. If you are experiencing symptoms like cold sores, fever, or flu-like illness, your doctor may recommend further evaluation to check for an active infection.

When This Test Might Be Ordered

Your doctor may order this test if you have symptoms of HSV-1 infection, such as cold sores, or if you have a history of cold sores. It can also be part of a general health checkup or if you have concerns about viral exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 Antibody Screen

Frequently asked questions

How long does it take to get the results of this test?
Results are typically available within a few days to a week, depending on your healthcare provider’s lab processes. Your doctor will discuss the results with you during your follow-up visit.
Can I have a follow-up test to confirm if I have an active HSV-1 infection?
Yes, if your initial antibody test is positive, your doctor may recommend additional testing, such as a viral culture or PCR test, to check for an active infection. These tests can confirm whether you are currently experiencing symptoms caused by HSV-1.
What are the possible side effects of this blood test?
Most people experience only minor side effects, such as a slight bruise, swelling, or soreness at the injection site. Rarely, there may be a slight fever or headache. If you experience severe pain or signs of infection (like redness, warmth, or pus), contact your healthcare provider immediately.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy