Herpes Simplex Virus 1 Antibody, Qualitative (IgG) in Serum or Plasma
This test checks for the presence of antibodies against Herpes Simplex Virus 1 (HSV-1), a common virus that can cause cold sores and other infections.
["It helps determine if your immune system has encountered HSV-1, which may affect future infection risk or symptoms."]
Key facts at a glance
- LOINC
- 44470-3
- Short code
- HSV1 Ag Anal Ql
- Synonyms
- HSV1 Ag Anal Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 86038
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects IgG antibodies specific to HSV-1, indicating past exposure to the virus. These antibodies are produced by your immune system in response to infection and can remain in your blood for years. This test is qualitative, meaning it only tells you whether antibodies are present or not, without providing a quantitative measure of their level.
Why It Might Be Ordered
Your healthcare provider may order this test if you have symptoms suggestive of HSV-1 infection (such as cold sores), if you have a history of recurrent cold sores, or if you are being evaluated for conditions where HSV-1 exposure could be relevant (e.g., certain immune disorders). It may also be used as part of a broader evaluation for sexually transmitted infections.
What to Expect Before the Test
No special preparation is needed for this test. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. If you are taking blood thinners or have a history of bleeding disorders, inform your healthcare provider beforehand.
What to Expect During the Test
The blood sample is collected and sent to a laboratory for analysis. The test uses an immunoassay method to detect the presence of HSV-1 antibodies. Results are typically available within a few days.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HSV-1 Antibody Screen
Frequently asked questions
Does this test show if I currently have an active HSV-1 infection?
Can I get HSV-1 from this test?
What does it mean if my test is negative?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy