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Herpes Simplex Virus Type 1 Antibody, Genital Site (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the herpes simplex virus type 1 (HSV-1), which can help identify past or current infection, especially in the genital region.

Quick summary

["This test may be used to confirm exposure to HSV-1, particularly if you have symptoms or risk factors for genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31846-9
Short code
HSV1 Ag Genital Ql
Synonyms
HSV1 Ag Genital Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge in the genital area, or if you have a history of HSV-1 exposure. It can also be used to screen for past infection in individuals with no current symptoms.

What to Expect During the Test

A small blood sample is typically taken from a vein in your arm. You may feel a brief pinch, but it usually doesn’t cause discomfort. The sample is then sent to a lab for antibody detection using an immunoassay method.

Sample Collection and Preparation

No special preparation is needed for this test. You may continue with your normal activities, but avoid taking any medications that might interfere with the results unless instructed otherwise.

What the Results Mean

Positive results indicate the presence of HSV-1 antibodies, suggesting past infection. Negative results mean no detectable antibodies were found at this time. Results alone do not confirm active infection; clinical symptoms and medical history are also considered.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 Antibody (Genital)

Frequently asked questions

What does a positive result mean?
A positive result suggests you have been exposed to HSV-1 at some point, meaning you may have had the virus in the past. This does not necessarily mean you currently have an active infection, but it does increase your risk for future outbreaks if symptoms develop.
How does this test differ from a viral load test?
This test measures antibodies, which indicate past exposure, while a viral load test measures the amount of active virus in your body. Viral load tests are used to monitor active infection and response to treatment.
Can this test be used to diagnose active genital herpes?
No, this test alone cannot diagnose an active genital herpes infection. Active infection is typically diagnosed through clinical symptoms, physical examination, or a separate viral culture or PCR test for HSV-1 DNA in a current lesion.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy