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Herpes Simplex Virus Type 1 Antibody, Serum (Qualitative/Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the herpes simplex virus type 1 (HSV-1), which can help identify past or current infection with this common virus.

Quick summary

["This test helps determine if you’ve been exposed to HSV-1, which can cause cold sores or other symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31848-5
Short code
HSV1 Ag Spec Ql
Synonyms
HSV1 Ag Spec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test looks for antibodies (proteins produced by your immune system) against HSV-1 in your blood. These antibodies develop after infection and can stay in your system for years. The test is qualitative (yes/no) or quantitative (measuring exact levels), depending on the lab’s method.

Why Might You Need This Test?

Your doctor may recommend this test if you have symptoms like cold sores, recurrent mouth ulcers, or if you’ve been exposed to someone with HSV-1. It can also be used for screening in certain high-risk groups or during pregnancy to assess risk.

What to Expect Before the Test

No special preparation is needed. You’ll have a simple blood draw, usually from your arm. The test is usually done in a lab and results are ready within a few days to a week, depending on the lab.

What Are the Possible Results?

A positive result means your body has produced antibodies against HSV-1, suggesting past infection. A negative result means no detectable antibodies were found at this time. Follow-up testing may be needed if symptoms persist.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 Antibody Test

Frequently asked questions

How long does it take to get results from this test?
Results typically take between a few days to a week, depending on the lab’s processing time. Your healthcare provider will contact you once they have the results.
Can I get HSV-1 from this test?
No, the test only looks for antibodies in your blood. It does not expose you to the virus. If you’re concerned about infection, avoid contact with anyone who has active cold sores.
Does this test show if I currently have an active infection?
This test primarily detects past infection by measuring antibodies. If you have active symptoms (like cold sores), your doctor may recommend additional testing or monitoring to check for active virus presence.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy