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Herpes Simplex Virus 1 Antibody, Qualitative (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the herpes simplex virus type 1 (HSV-1), which can help determine past or current infection.

Quick summary

["This test helps assess exposure to HSV-1, often used in diagnosing or monitoring conditions linked to the virus."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44477-8
Short code
HSV1 Ag Vag Ql
Synonyms
HSV1 Ag Vag Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for specific antibodies (IgG) produced by your immune system in response to HSV-1. If these antibodies are present, it suggests you have been exposed to the virus at some point, even if you don’t currently have active symptoms.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like cold sores, recurrent oral or genital sores, or if you’re at higher risk for HSV-1 (e.g., due to sexual history, immune conditions, or exposure). It can also be used in research or for screening in certain populations.

What to Expect Before the Test

No special preparation is needed. The blood sample is typically drawn from a vein in your arm. If you’re concerned about discomfort, let your provider know.

What the Results Mean

A positive result means antibodies to HSV-1 are present, indicating past exposure. A negative result suggests no detectable antibodies, meaning you may not have been exposed or the test may not have detected early infection. Results alone don’t confirm active infection—additional testing may be needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 Antibody Test

Frequently asked questions

Will this test show if I currently have HSV-1?
No, this test only detects antibodies produced by your immune system after exposure. For active infection, your provider may order additional tests.
How long does it take to get results?
Results are usually available within 2–5 business days, depending on lab processing times.
Can I have false positives or negatives?
While rare, false results can occur due to test limitations or timing (e.g., early infection). Discuss your results with your provider for interpretation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy