Skip to content

Herpes Simplex Virus Type 1 Antibody, Qualitative (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the herpes simplex virus type 1 (HSV-1) in your blood, helping identify past infection with this common virus.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-1, which can cause cold sores or other infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94835-6
Short code
HSV1 DNA Amn NAA+probe-Log#
Synonyms
HSV1 DNA Amn NAA+probe-Log#
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for IgG antibodies specific to HSV-1, which develop after your body has been exposed to the virus. These antibodies indicate a past infection rather than an active one. The result is qualitative, meaning it only tells you whether antibodies are present or not.

Why It’s Done

Doctors may order this test if you have recurrent cold sores, have had cold sores in the past, or if you’re being evaluated for conditions where HSV-1 exposure could be relevant, such as certain neurological disorders.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, typically in your arm. You may feel a slight pinch, but it usually takes a few minutes to complete.

What the Results Mean

A positive result means your body has produced antibodies to HSV-1, suggesting past infection. A negative result means no detectable antibodies were found at this time. This does not rule out past infection if testing was done too soon after exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

HSV-1 Antibody (IgG) Qualitative

Frequently asked questions

Is this test accurate if I’ve never had cold sores?
Yes, a negative result means no detectable antibodies were found at the time of testing, but it doesn’t guarantee you’ve never been exposed. Antibodies may take weeks to develop after initial infection.
Can I get false results from this test?
While rare, false results can occur if you have an active HSV-1 infection (not just antibodies), or if the test was performed too early after exposure. Your doctor may recommend additional testing if needed.
Does this test help with managing active cold sores?
No, this test only detects past infection. If you have active cold sores, your doctor may recommend antiviral medications or other treatments, but this test alone won’t guide treatment for current symptoms.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy