Herpes Simplex Virus Type 1 Antibody, Qualitative (IgG) by Immunofluorescence Probe
This test detects antibodies to the herpes simplex virus type 1 (HSV-1), a common virus that can cause cold sores and other infections. It helps determine if your body has developed immunity to HSV-1.
["This test checks for past exposure to HSV-1, not whether you currently have an active infection."]
Key facts at a glance
- LOINC
- 44478-6
- Short code
- HSV1 DNA Amn Ql NAA+probe
- Synonyms
- HSV1 DNA Amn Ql NAA+probe
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like cold sores, recurrent mouth ulcers, or if you’ve been exposed to someone with HSV-1. It can also be used for screening in certain high-risk groups or as part of a broader evaluation for recurrent infections.
What to Expect Before the Test
No special preparation is needed. You’ll likely provide a blood sample, usually drawn from a vein in your arm. If you’re unsure about timing, ask your provider—some tests may be best taken at a specific time of day.
What the Test Results Mean
A positive result means your body has produced antibodies against HSV-1, indicating past exposure. A negative result suggests you either haven’t been exposed or your immune system hasn’t yet developed antibodies. This does not confirm an active infection.
Common Causes of Positive Results
A positive HSV-1 antibody test is most commonly due to past infection, even if you’ve never had symptoms. It can also appear after vaccination or exposure to the virus.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
While this test confirms past exposure to HSV-1, it does not diagnose an active infection. Active HSV-1 infections (like cold sores) are usually diagnosed through viral culture, PCR, or clinical symptoms. If you’re experiencing recurrent cold sores or other symptoms, discuss them with your provider to explore further testing or treatment options.
Short name
HSV-1 IgG Antibody (Qualitative)
Frequently asked questions
What does a positive result mean for my health?
Can I get this test if I’m pregnant?
How long does it take to get the results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy