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: Herpes Simplex Virus 1 DNA Probe Assay, Fluid

Published: August 9, 2026Updated: August 16, 2026

: This test looks for genetic material (DNA) from herpes simplex virus type 1 in a sample of body fluid using a DNA probe method.

Quick summary

[": A positive result means HSV-1 DNA was detected in the fluid sample, while a negative result means it was not detected."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49986-3
Short code
HSV1 DNA # Fld NAA+probe
Synonyms
HSV1 DNA # Fld NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Test Measures

: The test detects and identifies DNA from herpes simplex virus type 1, one of the two main herpes simplex viruses. DNA probes are laboratory tools that bind to a specific genetic sequence and signal its presence.

: Why It Is Ordered

: A healthcare provider may order this test when a herpes infection is suspected in a particular body fluid, or to help confirm whether symptoms are caused by HSV-1. It can support diagnosis when a sample from the affected area is collected.

: How the Sample Is Collected

: The sample is a body fluid, and the exact fluid depends on the clinical situation and the provider's request. Collection is performed by a healthcare professional using standard procedures for that fluid.

: What Results Mean

: A detected (positive) result indicates that HSV-1 DNA is present in the sample. A not-detected (negative) result means it was not found, though timing of collection and other factors can affect results. Results should be interpreted together with symptoms and other findings.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: HSV-1 DNA testing can help confirm the presence of herpes simplex virus type 1 in a fluid specimen and support clinical decision-making. Because detection depends on sampling and timing, results are best interpreted by a healthcare provider in the full context of the patient's history and examination.

Short name

: HSV-1 DNA

Frequently asked questions

: Does a positive result always mean I have an active infection?
: A positive result shows that HSV-1 DNA was detected in the sample. Your provider will interpret this along with your symptoms and history to determine what it means for you.
: What type of sample is used for this test?
: This test uses a body fluid sample. The specific fluid is chosen by your healthcare provider based on your situation.
: Can this test tell HSV-1 apart from HSV-2?
: Yes. This test specifically targets herpes simplex virus type 1 DNA, so it is designed to distinguish HSV-1 from HSV-2.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy