Herpes Simplex Virus Type 1 DNA (Quantitative) in Saliva
This test measures the amount of genetic material from the herpes simplex virus type 1 (HSV-1) in your saliva. It helps determine if you have an active infection or have been exposed to the virus.
["This test helps diagnose or monitor herpes simplex virus type 1 infection in saliva samples."]
Key facts at a glance
- LOINC
- 80353-6
- Short code
- HSV 1 DNA pol regB+TK regC Anogn Ql NAA+pr
- Synonyms
- HSV 1 DNA pol regB+TK regC Anogn Ql NAA+pr
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual rashes in the mouth or genital area that could be caused by HSV-1. It may also be used to confirm a diagnosis in cases where symptoms are unclear or to check for infection in individuals without obvious symptoms, such as newborns or those with weakened immune systems.
What to Expect Before the Test
No special preparation is needed. You will provide a saliva sample, typically collected by swabbing your inner cheek or spitting into a container. This is usually done in a clinical setting or at home if instructed.
What the Test Results Mean
Positive results indicate the presence of HSV-1 DNA, suggesting active infection. Negative results mean no detectable virus DNA was found in the sample. The presence of HSV-1 DNA does not distinguish between active infection and past infection.
Common Symptoms of HSV-1 Infection
HSV-1 often causes cold sores or fever blisters around the mouth and face. Some people may have no symptoms at all, but the virus can still be present and spread. Symptoms can include tingling, burning, or pain before sores appear, followed by red, swollen areas that develop into blisters.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
This test is crucial for diagnosing HSV-1 infections early, especially in cases where symptoms are mild or atypical. It helps guide treatment decisions, such as antiviral medications, and can inform decisions about close contacts to prevent transmission. Regular monitoring with this test may also be important for individuals with recurrent infections or those managing chronic conditions like HIV.
Short name
HSV-1 DNA Test (Saliva)
Frequently asked questions
How long does it take to get the results of this test?
Can this test detect past infection from HSV-1?
Is there any risk or discomfort associated with this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy