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Herpes Simplex Virus Type 1 (HSV-1) Antibody, Qualitative Skin Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to the herpes simplex virus type 1 (HSV-1) using a skin probe method, which helps identify past or current infection by HSV-1.

Quick summary

["This test may help determine if you’ve been exposed to HSV-1, though it doesn’t confirm active infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92871-3
Short code
HSV1 DNA Skin Ql NAA+probe
Synonyms
HSV1 DNA Skin Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test involves applying a probe to your skin to detect HSV-1 antibodies, which your immune system produces after exposure. This method is qualitative, meaning it only tells you if antibodies are present rather than how much.

How the Test Works

A small probe is placed on your skin (often the arm or thigh) to detect immune responses. If antibodies are found, a reaction may appear at the probe site, indicating past exposure to HSV-1.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms suggestive of HSV-1 (e.g., cold sores, fever blisters) or if you’ve had close contact with someone who has HSV-1. It’s also used in certain screening or research contexts.

What to Expect Before the Test

No special preparation is needed. You may experience mild redness or itching at the probe site, but this is normal and temporary.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps confirm exposure to HSV-1 but does not distinguish between past infection and current symptoms. Positive results indicate prior exposure, while negative results suggest no detectable antibodies. It’s useful for research, screening, or confirming exposure in specific clinical scenarios.

Short name

HSV-1 Antibody Skin Test (Qualitative)

Frequently asked questions

How accurate is this test?
This is a qualitative test, meaning it provides a yes/no result for antibody presence. Accuracy depends on proper application and may vary if the probe isn’t used correctly. It’s not designed to diagnose active infection but can indicate past exposure.
Can this test be used to diagnose active herpes?
No, this test does not diagnose active herpes (e.g., cold sores). For active infection, your provider may order viral culture, PCR, or other tests to confirm HSV-1 presence in lesions.
What does a positive result mean?
A positive result means your immune system has detected HSV-1 antibodies, suggesting past exposure. This does not guarantee you have active symptoms or disease but may indicate you’ve been infected at some point.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy