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Herpes Simplex Virus Type 1 IgG Antibody (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to the herpes simplex virus type 1 (HSV-1), which can indicate past infection with this common virus.

Quick summary

["Past exposure to HSV-1 may be detected through antibody testing, even if you don’t currently have symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48399-0
Short code
HSV1 gG IgG CSF-aCnc
Synonyms
HSV1 gG IgG CSF-aCnc
Category
glucose
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects IgG antibodies specific to HSV-1, which your immune system produces after an initial infection. These antibodies remain in your blood for years, helping your body recognize and fight the virus if it reappears. This test is typically done on serum or plasma from a blood sample.

Why It’s Done

Doctors may order this test if you have symptoms like cold sores, genital sores, or neurological issues (such as meningitis) that could be linked to HSV-1. It may also be used in research or to monitor immune response in certain conditions.

Sample Collection

A small amount of blood is drawn from your arm using a needle. The blood is then processed to separate serum or plasma for testing. This process is quick and usually causes minimal discomfort.

What to Expect Before or After

There are no special preparations needed for this test. You may experience mild bruising or soreness at the injection site, but these effects are temporary. If you have a bleeding disorder or take blood-thinning medications, let your doctor know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody

Frequently asked questions

Will this test show if I currently have HSV-1?
No, this test only detects past exposure through antibodies. If you have active symptoms (like sores), your doctor may order a different test to check for active infection.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy