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Herpes Simplex Virus Type 1 Immunoglobulin G Antibody (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against the herpes simplex virus type 1 (HSV-1) in your blood. These antibodies indicate whether your immune system has encountered HSV-1 before.

Quick summary

["This test helps determine past exposure to HSV-1, which can inform healthcare providers about your risk for recurrent infections or related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16948-2
Short code
HSV1 IgG CSF-aCnc
Synonyms
HSV1 IgG CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or fatigue that suggest a past HSV-1 infection, or if you’re evaluating for conditions linked to HSV-1 exposure, such as certain neurological disorders or immune system assessments.

What to Expect During the Test

A small blood sample is drawn from a vein, usually in your arm. You may feel a slight pinch, but it’s quick and typically not painful. The sample is then sent to a lab for analysis.

What the Results Mean

Positive results suggest your immune system has recognized HSV-1 antibodies, meaning you likely had exposure to the virus at some point. Negative results indicate no detectable antibodies, meaning no prior exposure was identified in this test.

Common Reasons for Testing

This test is often used in research or specialized evaluations to assess immune responses, screen for past infections, or investigate conditions where HSV-1 exposure may play a role, such as in certain autoimmune or neurological studies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody

Frequently asked questions

How long does it take to get the results of this test?
Results are typically available within 1 to 3 business days, depending on the lab’s processing schedule. Your healthcare provider will contact you once they have the results.
Can I get this test if I have an active HSV-1 infection?
This test measures antibodies, which are part of your immune response to past exposure. If you have an active infection, your provider may recommend a different test to assess viral load or activity.
Is there anything I should do to prepare for this test?
No special preparation is needed. However, inform your healthcare provider about any medications you’re taking, as some may affect lab results indirectly.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy