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Herpes Simplex Virus Type 1 Immunoglobulin G Antibody (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies to herpes simplex virus type 1 (HSV-1) in your blood. Antibodies are proteins your immune system makes in response to infection or vaccination.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-1, a virus that can cause cold sores or genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7909-5
Short code
HSV1 IgG Ser-aCnc
Synonyms
HSV1 IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The HSV-1 IgG antibody test detects immunoglobulin G (IgG) antibodies, which develop after your body has been exposed to HSV-1. Unlike IgM antibodies (which appear shortly after infection), IgG antibodies remain in your system for a longer period, indicating past exposure rather than an active infection.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms of HSV-1 infection (such as cold sores or genital sores), if you’ve had repeated outbreaks, or if you’re being evaluated for potential transmission to others. It can also be used in certain research or screening contexts.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, similar to other routine blood tests. The process usually takes a few minutes.

What to Expect After the Test

After the blood draw, you may feel slight discomfort or bruising at the site. Apply gentle pressure to stop any bleeding, and avoid rubbing the area. Most people return to their normal activities immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody

Frequently asked questions

What does a positive result mean?
A positive result means your body has produced antibodies against HSV-1, indicating you’ve likely been exposed to the virus at some point. This does not mean you currently have an active infection, but it confirms past exposure.
Can this test tell me if I have an active herpes infection?
No, this test alone cannot diagnose an active herpes infection. If you suspect you have an active outbreak, your healthcare provider may recommend additional tests, such as viral culture or PCR, to confirm the current infection.
How long does it take to get the results?
Results are typically available within 1 to 3 business days, depending on your laboratory’s processing time. Your healthcare provider will contact you with the results once they are ready.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy