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Herpes Simplex Virus Type 1 Immunoglobulin M Antibody (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of Immunoglobulin M (IgM) antibodies against Herpes Simplex Virus Type 1 (HSV-1) in your blood. IgM antibodies are typically produced shortly after infection and can help identify recent exposure to the virus.

Quick summary

["IgM antibodies may indicate recent HSV-1 infection, aiding in diagnosis when other symptoms or tests are present."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7910-3
Short code
HSV1 IgM Ser-aCnc
Synonyms
HSV1 IgM Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgM antibodies are a type of antibody your immune system produces in response to an infection. In this test, we detect these antibodies specific to HSV-1, which is the virus responsible for causing cold sores and oral herpes. IgM antibodies usually appear early in the infection and can help determine if you have recently been exposed to HSV-1.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like sores, blisters, or pain in your mouth, lips, or genitals that suggest herpes infection. It may also be used to confirm a suspected diagnosis when other tests or symptoms are present, especially if you have no history of previous infections.

What Does a Positive Result Mean?

A positive result means your blood contains IgM antibodies against HSV-1, suggesting you likely had a recent infection. This does not necessarily mean you are currently experiencing symptoms, as some people may not show signs of illness. It’s important to discuss your results with your healthcare provider for further guidance.

What Does a Negative Result Mean?

A negative result means your blood did not contain detectable IgM antibodies against HSV-1 at the time of testing. This could mean you either have not been recently infected or the infection was not severe enough to produce detectable IgM antibodies. Follow-up testing or clinical evaluation may still be needed to assess your situation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgM Antibody

Frequently asked questions

How is this test performed?
This test involves drawing blood from a vein in your arm. A small amount of blood is collected and sent to a lab for analysis using an immunoassay method to detect HSV-1 IgM antibodies.
What can affect this test?
Several factors may influence test results, including the timing of the blood draw relative to when symptoms first appeared, the presence of other infections, or medications that could interfere with antibody detection. If you suspect recent exposure or have symptoms, it’s important to inform your healthcare provider about any recent illnesses or treatments.
Can this test be done at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home testing kits are not available for this specific test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy