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Herpes Simplex Virus Type 1 Immunoglobulin G (IgG) Antibody, Titration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against herpes simplex virus type 1 (HSV-1) in your blood. Antibodies are your body’s natural defense against infections.

Quick summary

["This test helps determine if you’ve been exposed to HSV-1, which can cause cold sores or other infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22334-7
Short code
HSV1 IgM Titr CSF
Synonyms
HSV1 IgM Titr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like cold sores, recurrent mouth sores, or if you’ve been exposed to someone with HSV-1. It may also be used to confirm a diagnosis or monitor immune response after treatment.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test is quick and typically done in a clinic or lab.

What the Results Mean

Positive results indicate the presence of HSV-1 antibodies, suggesting past or current infection. Negative results mean no detectable antibodies, but this doesn’t always rule out infection if testing was done too early.

Common Causes of Positive Results

A positive result can occur after exposure to HSV-1, even if you don’t currently have symptoms. It may also appear after vaccination or treatment with antiviral medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 1–3 business days, depending on your lab’s processing time.
Can I have false-positive or false-negative results?
False positives are rare but possible, especially if testing too soon after exposure. False negatives can occur if testing was done too early or if the infection was mild. Your healthcare provider will consider all results in context.
Does this test help with treatment decisions?
While this test confirms exposure to HSV-1, treatment decisions are based on symptoms and clinical evaluation. Antiviral medications can help manage outbreaks or prevent complications, but they’re not used solely based on antibody levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy