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Herpes Simplex Virus 1 Immunoglobulin G (IgG) Antibody, Titrated

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to the herpes simplex virus type 1 (HSV-1), which causes cold sores and can also affect other parts of the body. Antibodies indicate past infection or immunity.

Quick summary

["This test helps determine if you’ve been exposed to HSV-1 or if your immune system has developed protection against it."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14087-1
Short code
HSV1 IgM Titr CSF IF
Synonyms
HSV1 IgM Titr CSF IF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Matters

Herpes simplex virus type 1 (HSV-1) is a common virus that can cause cold sores around the mouth and lips. While many people have been exposed to it, some may not show symptoms. This test helps doctors understand whether you have developed immunity or if you might need further evaluation for active infection.

How the Test Works

Your blood sample is tested using an immunoassay method to detect specific antibodies (IgG) against HSV-1. The result is reported as a numerical value indicating the concentration of these antibodies, which helps assess past exposure or immunity.

What the Results Mean

A positive result means your body has produced antibodies against HSV-1, suggesting past infection. The exact concentration (titration) can provide additional context about your immune response. A negative result means no detectable antibodies were found, which may indicate no prior exposure or recent infection.

Common Reasons for Testing

Doctors may order this test if you have symptoms of HSV-1 (e.g., cold sores), if you’re planning pregnancy and have concerns about viral infections, or if you’re evaluating immune function in certain conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-1 IgG Antibody (Titrated)

Frequently asked questions

What does a high or low antibody level mean?
A high antibody level suggests you’ve likely had HSV-1 infection at some point and may have immunity. However, antibodies do not always correlate with current infection status. If you have symptoms, further testing may be needed to check for active virus.
Can this test detect active herpes infection?
No, this test only measures antibodies, which indicate past exposure or immunity. To check for active herpes infection, your doctor may recommend additional tests, such as viral culture or PCR.
How long does it take to get results?
Results are typically available within 24 to 72 hours, depending on your lab’s processing schedule. Follow-up with your healthcare provider to discuss the meaning of your results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy