Herpes Simplex Virus 2 Antibody, Total (Serum/Plasma)
This test measures the presence of antibodies against herpes simplex virus type 2 (HSV-2) in your blood. Antibodies are your body’s immune response to past or current infection.
["This test helps determine if you’ve been exposed to HSV-2 or if you have an active infection."]
Key facts at a glance
- LOINC
- 44493-5
- Short code
- HSV2 Ab CSF Ql
- Synonyms
- HSV2 Ab CSF Ql
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge, especially in the genital area. It’s also used to confirm a diagnosis of genital herpes caused by HSV-2, screen for past exposure, or check for recurrence of symptoms. Sometimes, it’s part of a routine checkup for individuals at higher risk of sexually transmitted infections.
What to Expect During the Test
A small amount of blood is drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause much discomfort. The blood is then sent to a lab for testing. Results are typically available within a few days.
Understanding Your Results
If your test is positive, it means your body has detected antibodies to HSV-2, indicating past exposure or infection. A negative result means no detectable antibodies were found at this time. Remember, a negative result doesn’t guarantee you’re completely free of HSV-2, as testing may not always detect early or inactive infections.
What It Means for Your Health
Having HSV-2 antibodies can affect how you manage your health and relationships. If you’re diagnosed with HSV-2, your healthcare provider may recommend antiviral medications to manage symptoms, reduce outbreaks, and lower the risk of transmitting the virus to others. Regular follow-ups and open communication with your provider are important to monitor your health and address any concerns.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
HSV-2 Antibody Test
Frequently asked questions
How often will I need to get this test?
Can I have false-positive or false-negative results?
Does this test show if I currently have an active infection?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy