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Herpes Simplex Virus Type 2 Antibody Pattern Serum Immunoassay

Published: August 9, 2026Updated: August 17, 2026

This test detects antibodies to herpes simplex virus type 2 (HSV-2) in your blood, helping identify past or current infection.

Quick summary

["This test helps determine if you’ve been exposed to HSV-2, which can cause genital herpes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
13501-2
Short code
HSV2 Ab pattern Ser-Imp
Synonyms
HSV2 Ab pattern Ser-Imp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test measures different types of antibodies your immune system produces in response to HSV-2. These antibodies can indicate whether you’ve had exposure to the virus at some point, even if you don’t currently have symptoms.

Why Might You Need This Test?

Doctors may recommend this test if you have symptoms like sores or lesions around your genitals, mouth, or rectum; if you have a history of genital herpes; or if you’re at higher risk for HSV-2 (e.g., due to sexual history or medical conditions). It can also be used during pregnancy to assess risk for transmission to your baby.

What Does a Positive Result Mean?

A positive result means your body has detected antibodies to HSV-2, suggesting past exposure. However, it doesn’t confirm whether you’re currently infected or if symptoms are active. Testing for viral load (active virus) may be needed for diagnosis of active herpes.

What Does a Negative Result Mean?

A negative result means your blood sample did not show detectable antibodies to HSV-2 at this time. This could mean you’ve never been exposed, or if you were, your immune system cleared the virus without leaving detectable antibodies.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding Your Results

Short name

HSV-2 Antibody Test

Frequently asked questions

How Long Does It Take to Get Results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Follow-up with your healthcare provider for interpretation.
Can This Test Detect Active Herpes?
No, this antibody test alone cannot confirm active herpes. If you suspect an active infection, your doctor may recommend additional testing, such as viral culture or PCR (polymerase chain reaction) for HSV-2 DNA.
What If I Have Recurrent Symptoms?
If you experience recurrent sores or symptoms, discuss this with your healthcare provider. They may recommend retesting for HSV-2 antibodies or other diagnostic tests to guide treatment or management strategies.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy