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Herpes Simplex Virus Type 2 Antibody, Serum (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to herpes simplex virus type 2 (HSV-2), which causes genital herpes. Antibodies indicate past or current infection.

Quick summary

["This test helps determine if you’ve ever been exposed to HSV-2 or if you currently have an infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
7911-1
Short code
HSV2 Ab Ser-aCnc
Synonyms
HSV2 Ab Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sores, pain, or unusual discharge in the genital area, or if you have recurrent outbreaks. It can also be used for screening, especially in high-risk groups like those with multiple sexual partners or a history of sexually transmitted infections (STIs).

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample from a vein in your arm. The test is usually done in a lab setting and may take a few minutes.

What the Test Results Mean

A positive result means you have antibodies to HSV-2, suggesting past infection. A negative result means no detectable antibodies, but it doesn’t rule out current infection (since antibodies may take time to develop). If you’re concerned, discuss your symptoms and test results with your provider.

Possible Results and Next Steps

If you test positive, your provider may recommend further testing to confirm HSV-2 infection (rather than HSV-1) and discuss treatment options, such as antiviral medications. If you test negative but have symptoms, other causes may be investigated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

HSV-2 is a common sexually transmitted infection that can cause painful sores and recurrent outbreaks. Antibody testing helps diagnose past infection, assess risk, and guide management. Early treatment can reduce symptoms and transmission.

Short name

HSV-2 Antibody Test

Frequently asked questions

Will this test show if I currently have an active infection?
No, this test measures antibodies, which develop after infection. If you have active symptoms, your provider may recommend additional testing, such as viral culture or PCR, to confirm current infection.
Can I get this test if I’m pregnant?
Yes, HSV-2 antibody testing is often recommended during pregnancy to assess risk of transmission to the baby. Your provider will discuss the results and any necessary steps with you.
What if I have a false-positive result?
False positives are rare but possible. If you have a positive result, your provider may repeat the test or use other methods to confirm the diagnosis. They’ll help clarify the next steps based on your symptoms and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy