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Herpes Simplex Virus Type 2 Antibody, Serum (Qualitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to herpes simplex virus type 2 (HSV-2), which causes genital herpes. Antibodies indicate past or current infection.

Quick summary

["This test helps determine if you’ve been exposed to genital herpes virus."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5208-4
Short code
HSV2 Ab Ser IA-aCnc
Synonyms
HSV2 Ab Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have symptoms like sores or lesions in the genital area, or if you have a history of genital herpes. It can also be used during pregnancy to check for infection in the mother.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample from a vein in your arm. It usually takes a few minutes.

What the Test Results Mean

A positive result means you have antibodies to HSV-2, suggesting past infection. A negative result means you likely haven’t been infected with this specific virus at the time of testing.

Common Reasons for Testing

This test is often used to diagnose genital herpes, especially if symptoms are unclear or if you have recurrent outbreaks. It can also help assess risk for transmission to others or during pregnancy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

HSV-2 Antibody Test

Frequently asked questions

What does a positive result mean?
A positive result means your body has detected antibodies to HSV-2, indicating past infection. This does not necessarily mean you currently have active symptoms, but it confirms exposure to the virus.
Can this test detect active herpes sores?
No, this test only detects antibodies, which indicate past or current infection. For diagnosing active herpes sores, your provider may use a different test or swab of the sores.
How long after exposure might I get positive results?
Results may take weeks to develop after exposure. Some people develop antibodies sooner, while others may take longer. Follow-up testing may be needed if symptoms persist or if you suspect recent exposure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy